3-(2H-Tetrazol-5-yl)pyridine
98%
Reagent
Code: #194648
CAS Number
3250-74-6
science Other reagents with same CAS 3250-74-6
blur_circular Chemical Specifications
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Molecular Information
Weight
147.14 g/mol
Formula
C₆H₅N₅
thermostat
Physical Properties
Melting Point
240°C
Boiling Point
379.4°C
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Storage & Handling
Storage
Room temperature, dry
description Product Description
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, such as losartan and other sartan-class antihypertensive drugs. Its tetrazole ring mimics the carboxylic acid group in biological systems, enhancing metabolic stability and improving bioavailability. Commonly employed in pharmaceutical research to develop potent, selective agents for treating high blood pressure and cardiovascular diseases. Also utilized in coordination chemistry as a ligand due to its nitrogen-rich structure, forming stable complexes with metal ions for potential use in catalysis or material science.
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