((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-L-valine
Analytical control substance, 98%
Reagent
Code: #193476
CAS Number
676129-92-3
science Other reagents with same CAS 676129-92-3
blur_circular Chemical Specifications
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Molecular Information
Weight
351.4 g/mol
Formula
C₁₉H₂₁N₅O₂
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Storage & Handling
Storage
-20°C
description Product Description
Used primarily as an intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of antihypertensive drugs like valsartan. Its structure enables effective binding to biological targets involved in blood pressure regulation. This compound plays a critical role in developing medications that treat hypertension and heart failure by blocking the action of angiotensin II, a substance that narrows blood vessels. Its tetrazole group mimics the carboxylic acid functionality, enhancing metabolic stability and bioavailability in final drug formulations.
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