5-Phenyl-1-trityl-1H-tetrazole

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Reagent Code: #193182
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CAS Number 154750-11-5

science Other reagents with same CAS 154750-11-5

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Weight 388.46 g/mol
Formula C₂₆H₂₀N₄
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Storage Room temperature

description Product Description

Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of sartan-class antihypertensive drugs such as valsartan and losartan. It serves as a protected tetrazole building block, enabling selective reactions at other functional sites during multi-step pharmaceutical syntheses. Its trityl (triphenylmethyl) group provides stability and prevents unwanted side reactions, making it valuable in solid-phase and solution-phase peptide and heterocycle chemistry. Also employed in the development of novel bioactive molecules where the tetrazole ring acts as a bioisostere for carboxylic acid groups.

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inventory 5g
10-20 days ฿50,900.00

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5-Phenyl-1-trityl-1H-tetrazole
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Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of sartan-class antihypertensive drugs such as valsartan and losartan. It serves as a protected tetrazole building block, enabling selective reactions at other functional sites during multi-step pharmaceutical syntheses. Its trityl (triphenylmethyl) group provides stability and prevents unwanted side reactions, making it valuable in solid-phase and solution-phase peptide and heterocycle chemistry. Also employed in the development of novel bioactive molecules where the tetrazole ring acts as a bioisostere for carboxylic acid groups.
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