5-Phenyl-1-trityl-1H-tetrazole
98%
Reagent
Code: #193182
CAS Number
154750-11-5
science Other reagents with same CAS 154750-11-5
blur_circular Chemical Specifications
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Molecular Information
Weight
388.46 g/mol
Formula
C₂₆H₂₀N₄
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Storage & Handling
Storage
Room temperature
description Product Description
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of sartan-class antihypertensive drugs such as valsartan and losartan. It serves as a protected tetrazole building block, enabling selective reactions at other functional sites during multi-step pharmaceutical syntheses. Its trityl (triphenylmethyl) group provides stability and prevents unwanted side reactions, making it valuable in solid-phase and solution-phase peptide and heterocycle chemistry. Also employed in the development of novel bioactive molecules where the tetrazole ring acts as a bioisostere for carboxylic acid groups.
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