3-(5-Methyl-1H-tetrazol-1-yl)benzoic acid
98%
Reagent
Code: #193068
CAS Number
799262-37-6
science Other reagents with same CAS 799262-37-6
blur_circular Chemical Specifications
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Molecular Information
Weight
204.19 g/mol
Formula
C₉H₈N₄O₂
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Registry Numbers
MDL Number
MFCD04113966
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Storage & Handling
Storage
Room temperature
description Product Description
Used in the synthesis of angiotensin II receptor antagonists, particularly in the development of sartan-class antihypertensive drugs. The tetrazole ring serves as a bioisostere for the carboxylic acid group, enhancing metabolic stability and improving receptor binding affinity. It is a key intermediate in pharmaceuticals like candesartan and related compounds, contributing to their effectiveness in managing high blood pressure. Its structure allows for better oral bioavailability and longer duration of action in vivo.
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