3-(5-Methyl-1H-tetrazol-1-yl)benzoic acid

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Reagent Code: #193068
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CAS Number 799262-37-6

science Other reagents with same CAS 799262-37-6

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Weight 204.19 g/mol
Formula C₉H₈N₄O₂
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MDL Number MFCD04113966
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Used in the synthesis of angiotensin II receptor antagonists, particularly in the development of sartan-class antihypertensive drugs. The tetrazole ring serves as a bioisostere for the carboxylic acid group, enhancing metabolic stability and improving receptor binding affinity. It is a key intermediate in pharmaceuticals like candesartan and related compounds, contributing to their effectiveness in managing high blood pressure. Its structure allows for better oral bioavailability and longer duration of action in vivo.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿4,150.00

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3-(5-Methyl-1H-tetrazol-1-yl)benzoic acid
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Used in the synthesis of angiotensin II receptor antagonists, particularly in the development of sartan-class antihypertensive drugs. The tetrazole ring serves as a bioisostere for the carboxylic acid group, enhancing metabolic stability and improving receptor binding affinity. It is a key intermediate in pharmaceuticals like candesartan and related compounds, contributing to their effectiveness in managing high blood pressure. Its structure allows for better oral bioavailability and longer duration of action in vivo.
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