10-(2-(1H-Tetrazol-5-yl)ethyl)-2,7-dichloro-9,9-dimethyl-9,10-dihydroacridine

98%

Reagent Code: #191253
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CAS Number 1443290-89-8

science Other reagents with same CAS 1443290-89-8

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 374.27 g/mol
Formula C₁₈H₁₇Cl₂N₅
badge Registry Numbers
MDL Number MFCD32215313
thermostat Physical Properties
Boiling Point 586.8±60.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.357±0.06 g/cm3(Predicted)
Storage -20°C, Inert Gas

description Product Description

Used in pharmaceutical research as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the development of antihypertensive drugs. Its tetrazole moiety enhances bioavailability and mimics the carboxylic acid group in drug molecules, improving binding affinity to target receptors. Commonly employed in the preparation of sartan-class medications, where it contributes to the structural framework that blocks vasoconstriction and aldosterone release, helping manage high blood pressure. Also explored in medicinal chemistry for optimizing metabolic stability and pharmacokinetic profiles of new drug candidates.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿33,280.00
inventory 250mg
10-20 days ฿56,570.00

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10-(2-(1H-Tetrazol-5-yl)ethyl)-2,7-dichloro-9,9-dimethyl-9,10-dihydroacridine
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Used in pharmaceutical research as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the development of antihypertensive drugs. Its tetrazole moiety enhances bioavailability and mimics the carboxylic acid group in drug molecules, improving binding affinity to target receptors. Commonly employed in the preparation of sartan-class medications, where it contributes to the structural framework that blocks vasoconstriction and aldosterone release, helping manage high blood pressure. Also explored in medicinal chemistry for optimizing metabolic stability and pharmacokinetic profiles of new drug candidates.
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