10-(2-(1H-Tetrazol-5-yl)ethyl)-2,7-dichloro-9,9-dimethyl-9,10-dihydroacridine
98%
Reagent
Code: #191253
CAS Number
1443290-89-8
science Other reagents with same CAS 1443290-89-8
blur_circular Chemical Specifications
scatter_plot
Molecular Information
Weight
374.27 g/mol
Formula
C₁₈H₁₇Cl₂N₅
badge
Registry Numbers
MDL Number
MFCD32215313
thermostat
Physical Properties
Boiling Point
586.8±60.0 °C(Predicted)
inventory_2
Storage & Handling
Density
1.357±0.06 g/cm3(Predicted)
Storage
-20°C, Inert Gas
description Product Description
Used in pharmaceutical research as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the development of antihypertensive drugs. Its tetrazole moiety enhances bioavailability and mimics the carboxylic acid group in drug molecules, improving binding affinity to target receptors. Commonly employed in the preparation of sartan-class medications, where it contributes to the structural framework that blocks vasoconstriction and aldosterone release, helping manage high blood pressure. Also explored in medicinal chemistry for optimizing metabolic stability and pharmacokinetic profiles of new drug candidates.
shopping_cart Available Sizes & Pricing
Cart
No products
Subtotal:
0.00
Total
0.00
THB