5-(3-Fluorophenyl)-1H-tetrazole

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Reagent Code: #188694
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CAS Number 50907-20-5

science Other reagents with same CAS 50907-20-5

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 164.142 g/mol
Formula C₇H₅FN₄
badge Registry Numbers
MDL Number MFCD01075702
thermostat Physical Properties
Melting Point 142-144 °C
Boiling Point 335.5 °C at 760 mmHg
inventory_2 Storage & Handling
Storage Room temperature, seal, dry, inert gas

description Product Description

Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of sartan-class antihypertensive drugs such as losartan and valsartan. Its tetrazole ring serves as a bioisostere for the carboxylic acid group, enhancing metabolic stability and improving pharmacokinetic properties. Also employed in coordination chemistry as a ligand for metal ions in catalytic systems. Shows potential in the development of new pharmaceuticals due to its ability to participate in hydrogen bonding and dipole interactions with biological targets.

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Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿750.00
inventory 1g
10-20 days ฿1,680.00
inventory 5g
10-20 days ฿5,600.00

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5-(3-Fluorophenyl)-1H-tetrazole
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Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of sartan-class antihypertensive drugs such as losartan and valsartan. Its tetrazole ring serves as a bioisostere for the carboxylic acid group, enhancing metabolic stability and improving pharmacokinetic properties. Also employed in coordination chemistry as a ligand for metal ions in catalytic systems. Shows potential in the development of new pharmaceuticals due to its ability to participate in hydrogen bonding and dipole interactions with biological targets.
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