2-(2-fluoro-[1,1'-biphenyl]-4-yl)propanenitrile
95%
Reagent
Code: #188285
CAS Number
74648-00-3
science Other reagents with same CAS 74648-00-3
blur_circular Chemical Specifications
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Molecular Information
Weight
225.1 g/mol
Formula
C₁₅H₁₂FN
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Storage & Handling
Storage
2-8℃
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the production of angiotensin II receptor antagonists (sartans), which are widely prescribed for hypertension and cardiovascular diseases. Its fluorinated biphenyl structure enhances binding affinity and metabolic stability in active drug compounds. Commonly employed in the preparation of telmisartan and similar derivatives due to its ability to improve lipophilicity and bioavailability. Also utilized in research for developing new bioactive molecules with improved pharmacokinetic profiles.
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