5-(2-Fluorophenyl)-1H-tetrazole
97%
Reagent
Code: #188279
CAS Number
50907-19-2
science Other reagents with same CAS 50907-19-2
blur_circular Chemical Specifications
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Molecular Information
Weight
164.14 g/mol
Formula
C₇H₅FN₄
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Registry Numbers
MDL Number
MFCD00798373
thermostat
Physical Properties
Melting Point
160 - 162 °C
Boiling Point
331.8 ºC at 760 mmHg
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Storage & Handling
Density
1.403 g/cm3
Storage
Room temperature
description Product Description
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of sartan-class antihypertensive drugs such as losartan and valsartan. Its tetrazole ring mimics the carboxylic acid group in biological systems, enhancing binding affinity to the angiotensin II receptor. Also employed in coordination chemistry as a ligand due to its ability to form stable complexes with metal ions. Additionally, it finds use in the development of agrochemicals and in materials science for designing nitrogen-rich compounds.
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