Ethyl 2-(5-Methyl-1H-Tetrazol-1-Yl)Acetate
97%
science Other reagents with same CAS 81548-02-9
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description Product Description
Used as an intermediate in pharmaceutical synthesis, particularly in the production of angiotensin II receptor antagonists like losartan and other sartan-class drugs. The tetrazole ring mimics a carboxylic acid group, enhancing binding to biological targets, and this ethyl ester derivative serves as a protected or activated form during drug manufacturing. It enables efficient introduction of the tetrazole moiety under controlled reaction conditions, improving yield and selectivity in multi-step syntheses. Also employed in medicinal chemistry for developing bioisosteres in drug design.
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