1-(4-Ethoxyphenyl)-5-mercapto-1H-tetrazole
98%
Reagent
Code: #183167
CAS Number
15182-68-0
blur_circular Chemical Specifications
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Molecular Information
Weight
222.27 g/mol
Formula
C₉H₁₀N₄OS
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Storage & Handling
Storage
Room temperature
description Product Description
Used as an intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of sartan-class antihypertensive drugs like valsartan and losartan. Its thiol and tetrazole functionalities contribute to binding affinity with the angiotensin II receptor, enhancing drug efficacy. Also employed in medicinal chemistry for developing new bioactive molecules due to its ability to mimic carboxylic acid groups while improving metabolic stability and membrane permeability.
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