5-(2,5-Dichlorophenyl)-1H-tetrazole
≧95%
science Other reagents with same CAS 98555-71-6
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description Product Description
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of sartan-class antihypertensive drugs such as valsartan and losartan. Its tetrazole ring mimics the carboxylic acid group in biological systems, enhancing binding affinity to the angiotensin II receptor. Due to this property, it plays a crucial role in improving the potency and oral bioavailability of these medications. Also employed in coordination chemistry as a ligand for metal ions, forming stable complexes with potential applications in catalysis and material science.
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