5-(2-Phenoxyphenyl)-2H-tetrazole
95%
Reagent
Code: #173772
CAS Number
220429-69-6
blur_circular Chemical Specifications
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Molecular Information
Weight
238.24 g/mol
Formula
C₁₃H₁₀N₄O
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Registry Numbers
MDL Number
MFCD18911738
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Storage & Handling
Storage
2-8°C
description Product Description
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of antihypertensive drugs like valsartan and related sartan-class medications. Its tetrazole ring mimics the carboxylic acid group in biological systems, enhancing binding affinity to the angiotensin II receptor. Also employed in medicinal chemistry for developing new bioactive molecules due to its metabolic stability and ability to improve pharmacokinetic properties.
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