3-(2H-Tetrazol-5-yl)benzaldehyde
≥95%
Reagent
Code: #172924
CAS Number
136689-94-6
blur_circular Chemical Specifications
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Molecular Information
Weight
174.16 g/mol
Formula
C₈H₆N₄O
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Registry Numbers
MDL Number
MFCD18064602
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Storage & Handling
Storage
Room temperature, dry
description Product Description
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of sartan-class antihypertensive drugs like candesartan and valsartan. Its tetrazole ring mimics the carboxylic acid group in biological systems, enhancing binding affinity to the angiotensin II receptor. Commonly employed in pharmaceutical research and development for constructing bioactive molecules with improved metabolic stability and oral bioavailability. Also utilized in click chemistry and heterocyclic compound development due to the reactivity of the aldehyde and tetrazole functional groups.
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