2-(3',5'-Dichloro-[1,1'-biphenyl]-3-yl)acetic acid
95%
Reagent
Code: #171301
CAS Number
669713-80-8
blur_circular Chemical Specifications
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Molecular Information
Weight
281.13 g/mol
Formula
C₁₄H₁₀Cl₂O₂
thermostat
Physical Properties
Boiling Point
440.1±35.0°C
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Storage & Handling
Storage
Room temperature, dry
description Product Description
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of antihypertensive drugs like valsartan and related sartan-class medications. Its structure enables the formation of biaryl moieties essential for the pharmacological activity of these drugs. Widely utilized in pharmaceutical research and development for creating potent, selective blockers of the angiotensin II receptor, helping manage high blood pressure and reduce cardiovascular risk. Also employed in the optimization of drug candidates due to its metabolic stability and favorable binding properties.
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