5-(4-Chloro-3-methylphenyl)-2H-tetrazole
97%
Reagent
Code: #165219
CAS Number
885278-43-3
blur_circular Chemical Specifications
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Molecular Information
Weight
194.62 g/mol
Formula
C₈H₇ClN₄
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Registry Numbers
MDL Number
MFCD06738316
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Storage & Handling
Storage
2-8°C, Inert Gas
description Product Description
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of antihypertensive drugs like candesartan and similar sartan-class medications. Its tetrazole ring mimics the carboxylic acid group in biological systems, enhancing binding affinity to the AT1 receptor. Widely utilized in pharmaceutical development for its metabolic stability and bioavailability when incorporated into active drug molecules. Also employed in research for designing new bioactive compounds due to its favorable pharmacokinetic properties.
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