2-Chloro-5-(2H-tetrazol-5-yl)pyridine
95%
science Other reagents with same CAS 1224464-93-0
blur_circular Chemical Specifications
description Product Description
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of antihypertensive drugs like losartan and related sartan-class medications. Its tetrazole ring mimics the carboxylic acid group in biological systems, enhancing binding to the angiotensin II receptor. This compound plays a critical role in improving the potency and metabolic stability of these drugs. It is widely utilized in pharmaceutical research and development for cardiovascular therapies.
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