2-Boc-4'-(Bromomethyl)biphenyl

95%

Reagent Code: #145772
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CAS Number 114772-40-6

science Other reagents with same CAS 114772-40-6

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 347.25 g/mol
Formula C₁₈H₁₉BrO₂
thermostat Physical Properties
Boiling Point 437°C
inventory_2 Storage & Handling
Storage 2-8°C

description Product Description

Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the preparation of losartan and related sartan-class antihypertensive drugs. The bromomethyl group allows for nucleophilic substitution reactions, enabling the introduction of heterocyclic moieties, while the Boc-protected biphenyl scaffold provides stability and selectivity during multi-step syntheses. Commonly employed in pharmaceutical research and development for constructing complex biaryl structures with high functional group tolerance.

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Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿210.00
inventory 1g
10-20 days ฿162.00
inventory 5g
10-20 days ฿384.00

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2-Boc-4'-(Bromomethyl)biphenyl
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Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the preparation of losartan and related sartan-class antihypertensive drugs. The bromomethyl group allows for nucleophilic substitution reactions, enabling the introduction of heterocyclic moieties, while the Boc-protected biphenyl scaffold provides stability and selectivity during multi-step syntheses. Commonly employed in pharmaceutical research and development for constructing complex biaryl structures wit
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the preparation of losartan and related sartan-class antihypertensive drugs. The bromomethyl group allows for nucleophilic substitution reactions, enabling the introduction of heterocyclic moieties, while the Boc-protected biphenyl scaffold provides stability and selectivity during multi-step syntheses. Commonly employed in pharmaceutical research and development for constructing complex biaryl structures with high functional group tolerance.
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