5-[4’-Bromomethyl-(1,1’-biphenyl)-2-yl]-1-triphenylmethyltetrazole
96%
Reagent
Code: #144426
CAS Number
124750-51-2
blur_circular Chemical Specifications
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Molecular Information
Weight
557.48 g/mol
Formula
C₃₃H₂₅BrN₄
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Registry Numbers
MDL Number
MFCD00665221
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Storage & Handling
Storage
2~8℃, dry
description Product Description
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the preparation of sartan-class antihypertensive drugs. Its structure allows for the introduction of biphenyl and tetrazole moieties, which are critical for biological activity in blocking the angiotensin II receptor. The bromomethyl group enables alkylation reactions to form carbon-nitrogen or carbon-oxygen bonds, facilitating the assembly of complex drug molecules. Commonly employed in pharmaceutical research and development for optimizing potency and pharmacokinetic properties of cardiovascular medications.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Purity | 95.5-100 |
| Appearance | WHITE TO OFF-WHITE POWDER OR CRYSTALS |
| Infrared Spectrum | Conforms to Structure |
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