Trifluoroacetic acid

for HPLC, 0.1% in Water

Reagent Code: #93309
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Alias Trifluoroacetic acid (TFA); Trifluoroacetic acid
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CAS Number 76-05-1

science Other reagents with same CAS 76-05-1

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 114.02 g/mol
Formula C₂HO₂F₃
badge Registry Numbers
EC Number 200-929-3
MDL Number MFCD00004169
inventory_2 Storage & Handling
Storage room temperature

description Product Description

Trifluoroacetic acid is widely used in organic synthesis as a strong acid catalyst, particularly in peptide synthesis and the production of pharmaceuticals. It is employed to deprotect and remove t-butyl-based protecting groups from amino acids during peptide synthesis, ensuring high purity and yield. In the pharmaceutical industry, it serves as a solvent or reagent for various reactions, including esterifications and condensations. Additionally, it is utilized in analytical chemistry as a mobile phase additive in HPLC to improve separation efficiency. Its strong acidity and volatility make it suitable for applications in polymer chemistry, where it aids in the synthesis and modification of polymers. Trifluoroacetic acid is also used in the production of agrochemicals and dyes, where its reactivity and solubility properties are advantageous.

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Test Parameter Specification
Appearance Colorless clear liquid
Concentration 0.1
Infrared Spectrum Conforms to Structure

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Size Availability Unit Price Quantity
inventory 500ml
10-20 days ฿3,460.00
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Trifluoroacetic acid
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Trifluoroacetic acid is widely used in organic synthesis as a strong acid catalyst, particularly in peptide synthesis and the production of pharmaceuticals. It is employed to deprotect and remove t-butyl-based protecting groups from amino acids during peptide synthesis, ensuring high purity and yield. In the pharmaceutical industry, it serves as a solvent or reagent for various reactions, including esterifications and condensations. Additionally, it is utilized in analytical chemistry as a mobile phase additive in HPLC to improve separation efficiency. Its strong acidity and volatility make it suitable for applications in polymer chemistry, where it aids in the synthesis and modification of polymers. Trifluoroacetic acid is also used in the production of agrochemicals and dyes, where its reactivity and solubility properties are advantageous.
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