Ammonium formate is widely used in analytical chemistry as a mobile phase component in liquid chromatography, particularly in mass spectrometry (LC-MS). Its volatile nature allows for easy removal during the evaporation process, making it ideal for sample preparation and analysis. It is also employed as a buffering agent to maintain pH stability in various chemical reactions. In organic synthesis, it serves as a hydrogen donor in catalytic transfer hydrogenation reactions, facilitating the reduction of unsaturated compounds. Additionally, it is used in the production of formic acid and as a de-icing agent due to its ability to lower the freezing point of water. Its applications extend to the pharmaceutical industry, where it aids in the purification and isolation of compounds.