Clobetasol propionate
≥98.0%
Reagent
Code: #92927
Alias
Clobetasol propionate; 21-Chloro-9α-fluoro-11β,17α-dihydroxy-16β-methyl-1,4-pregnadiene-3,20-dione-17-propionate
CAS Number
25122-46-7
science Other reagents with same CAS 25122-46-7
blur_circular Chemical Specifications
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Molecular Information
Weight
466.97 g/mol
Formula
C₂₅H₃₂ClFO₅
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Registry Numbers
EC Number
246-634-3
MDL Number
MFCD00058499
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Storage & Handling
Storage
-20°C
description Product Description
Clobetasol propionate is widely used in dermatology for its potent anti-inflammatory and immunosuppressive properties. It is primarily applied topically to treat various skin conditions such as eczema, psoriasis, and dermatitis. The chemical works by reducing inflammation, itching, and redness, providing relief from discomfort associated with these conditions. It is also effective in managing lichen planus, a chronic inflammatory skin disorder. Due to its high potency, it is typically prescribed for short-term use to avoid potential side effects like skin thinning or systemic absorption. In some cases, it is used to treat scalp conditions, including severe dandruff or psoriasis, often formulated as a shampoo or solution for easier application.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Melting point | 196-200 |
| Purity (HPLC) | 98-100 |
| Specific Rotation (20°C, 1,4-Dioxane) | 99-103 |
| Appearance | White to off-white powder |
| Infrared Spectrum | Conforms to Structure |
| Solubility in CHCl3 | Colorless to faint yellow, clear, 50 mg/mL |
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