Lithium tert-butoxide is widely used as a strong base in organic synthesis, particularly in deprotonation reactions. It is highly effective in generating carbanions from weakly acidic compounds, making it valuable in the formation of carbon-carbon bonds. This chemical is commonly employed in the synthesis of complex organic molecules, including pharmaceuticals and fine chemicals. Additionally, it serves as a catalyst or reagent in various polymerization processes, aiding in the production of specialized polymers. Its sterically hindered nature also makes it useful in selective reactions where less bulky bases might lead to unwanted side products.