Used as a strong, non-nucleophilic base in organic synthesis, particularly in deprotonation reactions to generate carbanions. It is effective in the preparation of enolates from carbonyl compounds, which are key intermediates in aldol reactions. Additionally, it is employed in the synthesis of organosilicon compounds and as a reagent in the production of pharmaceuticals and fine chemicals. Its steric bulk makes it suitable for selective deprotonation in complex molecules.