Tetrabutylammonium hydroxide solution is widely used in organic synthesis as a phase-transfer catalyst. It facilitates the transfer of reactants between immiscible phases, enhancing reaction rates and yields. In analytical chemistry, it serves as an ion-pairing agent in chromatography, improving the separation and detection of compounds. The solution is also employed in the preparation of quaternary ammonium salts, which have applications in surfactants, disinfectants, and fabric softeners. Additionally, it is utilized in the synthesis of specialty chemicals and pharmaceuticals, where its strong basicity and solubility in organic solvents are advantageous.