Used as a strong, non-nucleophilic base in organic synthesis, particularly for deprotonating weakly acidic substrates. It is highly effective in generating carbanions, which are intermediates in various reactions like alkylations, acylations, and condensations. Commonly employed in the preparation of organolithium compounds and in the synthesis of complex molecules, including pharmaceuticals and fine chemicals. Its sterically hindered structure minimizes side reactions, making it a valuable reagent in selective transformations.