Potassium tert-butoxide is widely used as a strong base in organic synthesis, particularly in deprotonation reactions. It is highly effective in the formation of carbon-carbon bonds, such as in aldol condensations and Wittig reactions. In the pharmaceutical industry, it plays a crucial role in the synthesis of active pharmaceutical ingredients (APIs) by facilitating elimination and substitution reactions. Additionally, it is employed in the production of polymers and as a catalyst in the manufacture of specialty chemicals. Its non-nucleophilic nature makes it ideal for reactions where strong, sterically hindered bases are required. Due to its high sensitivity to moisture, it must be stored and used in a dry, anhydrous environment.