Poly(ethylene glycol) is widely used in pharmaceuticals as a solvent, binder, and lubricant in tablet formulations. It helps in improving the solubility and bioavailability of poorly soluble drugs. In the medical field, it is utilized in ointments, creams, and suppositories due to its moisturizing and soothing properties. It also serves as a base for many laxatives.

In industrial applications, it acts as a plasticizer, softening agents in various materials, and as a lubricant in manufacturing processes. It is also employed in the production of polyurethane foams and resins. Additionally, it is used in the textile industry as a softener and antistatic agent.

In biotechnology, it is used in cell fusion and protein crystallization processes. It is also a key component in the formulation of many personal care products, such as shampoos, conditioners, and lotions, due to its ability to retain moisture and enhance product texture.