Sulfathiazole is primarily used as an antibacterial agent to treat various infections caused by susceptible bacteria. It is commonly applied in veterinary medicine to manage bacterial infections in animals, particularly in livestock and pets. In human medicine, it has been utilized to treat urinary tract infections, respiratory infections, and skin conditions like burns or wounds. Additionally, it is incorporated into topical formulations, such as creams or ointments, to prevent or treat bacterial infections in superficial injuries. Its effectiveness against gram-positive and gram-negative bacteria makes it a versatile option in combating bacterial growth. However, its use has declined in recent years due to the emergence of antibiotic resistance and the development of newer antibiotics.