Used primarily in skincare, TCA Solution is applied for chemical peels to improve skin texture and appearance. It helps reduce fine lines, wrinkles, and acne scars by removing the outer layers of damaged skin. Commonly used for facial rejuvenation, it also treats hyperpigmentation, sun damage, and uneven skin tone. The depth of the peel can be controlled based on concentration, allowing for superficial to medium-depth treatment. It's often used in clinical settings under professional supervision due to its potency. TCA Solution also finds use in removing warts and improving the look of mild skin discolorations. Proper aftercare is essential to minimize irritation and support skin healing.

In some cases, TCA Solution is used in laboratory settings for protein precipitation or biological sample preparation, but its use in these applications requires careful control of concentration and environmental conditions.