Used as a solvent in organic synthesis, particularly in peptide coupling and polymer chemistry due to its ability to dissolve a wide range of organic and inorganic compounds. Enhances reaction rates in esterifications and acylations because of its strong hydrogen-bond donor properties. Employed in pharmaceutical manufacturing as a building block for fluorinated compounds, which often exhibit improved metabolic stability and bioavailability. Commonly used in NMR spectroscopy as a solvent for analyzing polar compounds. Also finds use in the formulation of liquid chromatography mobile phases for separating fluorinated molecules.