Used in neuroscience research to study nicotinic acetylcholine receptors due to its ability to modulate receptor activity. It is investigated for potential cognitive enhancement and neuroprotective effects, particularly in conditions like Alzheimer's disease and Parkinson's disease. Also explored for its anti-inflammatory properties in the central nervous system. Serves as a biomarker for tobacco exposure in clinical and forensic toxicology. Investigated in drug development for mood disorders and addiction treatment because of its long half-life and favorable safety profile compared to nicotine.