Polyamide powder (30-60 mesh) is a specialty adsorbent used in column chromatography for the separation and purification of organic compounds, particularly polar substances such as alkaloids, flavonoids, amino acids, and phenolic compounds.

It offers selective adsorption based on hydrogen bonding and dipole interactions, making it ideal for isolating natural products and pharmaceuticals. Polyamide is often employed in preparative chromatography where silica gel is insufficient for certain polar separations.

This reagent provides good flow properties and reusability, with the 30-60 mesh size suitable for standard column packing to achieve efficient resolution.