Piroxicam is widely used as a nonsteroidal anti-inflammatory drug (NSAID) for the management of pain, inflammation, and stiffness caused by conditions such as osteoarthritis and rheumatoid arthritis. It helps reduce swelling and joint pain, improving mobility in patients with chronic inflammatory joint diseases. It is also prescribed for acute musculoskeletal disorders, including sprains and strains, due to its analgesic and anti-inflammatory properties. In some cases, piroxicam is used to treat pain and inflammation associated with gout. The drug is available in oral, capsule, tablet, and topical forms, allowing flexible dosing options. Topical formulations are particularly useful for localized pain relief with reduced systemic side effects. Due to its long half-life, it is usually administered once daily, improving patient compliance.