Praziquantel is widely used in the treatment of parasitic worm infections, particularly schistosomiasis and liver fluke diseases. It is effective against a broad range of trematodes and cestodes, making it a key drug in mass drug administration programs in endemic regions. The compound works by causing severe spasms and paralysis of the parasite’s muscles, leading to detachment from host tissues and subsequent destruction by the immune system. Due to its high efficacy, safety, and low cost, praziquantel is the treatment of choice in both human and veterinary medicine for most schistosome and tapeworm infections. It is often administered as a single oral dose, which supports its use in large-scale public health campaigns.