Widely used as a support matrix in solid-phase synthesis, particularly in peptide and oligonucleotide manufacturing. Its high mechanical stability and functionalization capacity make it ideal for combinatorial chemistry and high-throughput screening. Also employed as a stationary phase in chromatography, especially in size-exclusion and ion-exchange systems due to its porous structure and chemical resistance. Commonly found in resin-based catalysts and scavenging applications where selective binding or release of molecules is required. Its cross-linked nature provides excellent swelling in organic solvents, enhancing reactivity and accessibility in synthetic processes.