N,N-Diisopropylethylamine solution
~2 M in 1-methyl-2-pyrrolidinone
science Other reagents with same CAS 7087-68-5
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description Product Description
Widely used as a non-nucleophilic base in organic synthesis, particularly in the formation of sensitive intermediates where strong but sterically hindered bases are required. Commonly employed in peptide coupling reactions to neutralize acids and promote amide bond formation without causing racemization. Also utilized in the preparation of pharmaceuticals, agrochemicals, and fine chemicals where controlled basic conditions are essential. Its low nucleophilicity minimizes unwanted side reactions, making it ideal for deprotonation steps in multi-step syntheses. Frequently chosen in industrial processes due to its effectiveness in aprotic solvents and compatibility with a wide range of functional groups.
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