Magnesium bis(hexamethyldisilazide)

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Reagent Code: #209907
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CAS Number 857367-60-3

science Other reagents with same CAS 857367-60-3

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 345.07 g/mol
Formula C₁₂H₃₆MgN₂Si₄
badge Registry Numbers
MDL Number MFCD11656057
thermostat Physical Properties
Melting Point 121-124 °C (lit.)
inventory_2 Storage & Handling
Storage Room temperature, inert gas

description Product Description

Widely used as a strong non-nucleophilic base in organic synthesis, enabling deprotonation of weakly acidic protons without promoting side reactions like nucleophilic attack or elimination. Commonly employed in the formation of enolates, especially for sensitive substrates where regioselectivity and stereocontrol are critical. Facilitates lithiation reactions when used in combination with organolithium reagents, enhancing reactivity and selectivity. Applied in the synthesis of pharmaceuticals, agrochemicals, and fine chemicals where precise base behavior is required. Also utilized in polymerization reactions as an initiator or catalyst modifier due to its thermal stability and solubility in nonpolar solvents.

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inventory 1g
10-20 days ฿5,570.00

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Magnesium bis(hexamethyldisilazide)
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Widely used as a strong non-nucleophilic base in organic synthesis, enabling deprotonation of weakly acidic protons without promoting side reactions like nucleophilic attack or elimination. Commonly employed in the formation of enolates, especially for sensitive substrates where regioselectivity and stereocontrol are critical. Facilitates lithiation reactions when used in combination with organolithium reagents, enhancing reactivity and selectivity. Applied in the synthesis of pharmaceuticals, agrochemic

Widely used as a strong non-nucleophilic base in organic synthesis, enabling deprotonation of weakly acidic protons without promoting side reactions like nucleophilic attack or elimination. Commonly employed in the formation of enolates, especially for sensitive substrates where regioselectivity and stereocontrol are critical. Facilitates lithiation reactions when used in combination with organolithium reagents, enhancing reactivity and selectivity. Applied in the synthesis of pharmaceuticals, agrochemicals, and fine chemicals where precise base behavior is required. Also utilized in polymerization reactions as an initiator or catalyst modifier due to its thermal stability and solubility in nonpolar solvents.

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