Magnesium bis(hexamethyldisilazide)
95%
science Other reagents with same CAS 857367-60-3
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description Product Description
Widely used as a strong non-nucleophilic base in organic synthesis, enabling deprotonation of weakly acidic protons without promoting side reactions like nucleophilic attack or elimination. Commonly employed in the formation of enolates, especially for sensitive substrates where regioselectivity and stereocontrol are critical. Facilitates lithiation reactions when used in combination with organolithium reagents, enhancing reactivity and selectivity. Applied in the synthesis of pharmaceuticals, agrochemicals, and fine chemicals where precise base behavior is required. Also utilized in polymerization reactions as an initiator or catalyst modifier due to its thermal stability and solubility in nonpolar solvents.
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