Widely used in industrial applications, morpholine serves as a corrosion inhibitor in steam and water systems, particularly in power plants and heating systems. It helps maintain pH stability in boiler water, preventing acidic corrosion of metal components. Due to its volatility and solubility, it distributes evenly throughout the system and neutralizes acidic byproducts like carbon dioxide and organic acids.

It is also employed as a solvent in gas scrubbing processes to remove sulfur dioxide and hydrogen sulfide from natural gas and refinery gases.

Morpholine functions as an intermediate in the synthesis of various chemicals, including rubber vulcanization accelerators, surfactants, pharmaceuticals, resins, and coatings, enhancing heat and moisture resistance.

In agriculture, it acts as a building block for certain fungicides and plant growth regulators. Additionally, it serves as a precursor for pesticides, drugs, and oil additives to prevent corrosion in pipes and boilers.

In laboratory settings, it functions as a buffering agent in biochemical and analytical applications, especially in electrophoresis and chromatography. Its ability to form complexes with metals makes it useful in metal cleaning and surface treatment processes.

Furthermore, it is used in the formulation of concrete admixtures to control setting time and improve workability.