Used as a progestin in hormonal contraceptives to prevent ovulation and regulate menstrual cycles. Commonly administered as an injectable depot formulation for long-term birth control. Employed in hormone replacement therapy to manage symptoms of menopause and protect the endometrium from estrogen-induced hyperplasia. Also utilized in the treatment of endometrial cancer, abnormal uterine bleeding, and certain cases of secondary amenorrhea. Has been used in palliative care for appetite stimulation in patients with cancer or AIDS-related wasting.