Lupeol is a pentacyclic triterpenoid widely studied for its anti-inflammatory, antioxidant, and anti-cancer properties. It is used in skincare formulations due to its ability to protect against UV-induced damage, support skin regeneration, and provide anti-aging benefits. The compound shows promise in inhibiting the growth of cancer cells, particularly in prostate, breast, pancreatic, liver, and colorectal cancers, by modulating signaling pathways involved in cell proliferation and apoptosis. It is also explored for its hepatoprotective effects, helping protect the liver from toxins and reducing markers of liver damage. In traditional medicine, lupeol-rich plant extracts are applied for wound healing and treating inflammatory conditions. Its natural occurrence in fruits and medicinal plants makes it a candidate for nutraceutical and functional food development aimed at promoting overall health and preventing chronic diseases.