Used as a strong base in organic synthesis, particularly for deprotonating weakly acidic protons in the preparation of various organic intermediates. Commonly employed in the lithiation of aromatic and heteroaromatic compounds, enabling carbon-carbon bond formation in pharmaceuticals and fine chemicals. Also utilized in the synthesis of functionalized organolithium reagents due to its high reactivity and selectivity under controlled conditions. Requires handling at low temperatures and inert atmosphere due to high sensitivity to moisture and air.