Used primarily as a reference standard in determining octane ratings for gasoline, isooctane serves as the 100-point benchmark in the octane scale due to its excellent resistance to engine knocking. It is a key component in fuel testing and quality control within the petroleum industry. Additionally, isooctane is employed as a non-polar solvent in laboratories for extractions and analytical procedures, especially in environmental and organic chemistry. Its low reactivity and high volatility also make it suitable for use in calibration gases and as a carrier solvent in some industrial processes.