Harpagoside is primarily known for its anti-inflammatory and analgesic properties, making it a key compound in herbal medicine for managing joint and musculoskeletal conditions. It is commonly used to support the treatment of osteoarthritis, where it helps reduce pain and improve joint mobility. Its mechanism involves inhibition of inflammatory mediators such as prostaglandins and cytokines. Harpagoside is also utilized in remedies for lower back pain and rheumatic conditions due to its natural origin and relatively mild side effect profile. Additionally, it has been explored for its potential to support digestive health and stimulate appetite, though its main application remains in inflammation-related disorders.