Florisil is widely used as an adsorbent in solid-phase extraction (SPE) and column chromatography for the separation and purification of various organic compounds. It is particularly effective in the cleanup of environmental samples, such as food extracts and water samples, prior to pesticide residue analysis. Due to its strong polar properties, Florisil efficiently retains polar interferences while allowing non-polar and moderately polar analytes to be eluted selectively. It is commonly applied in the analysis of fat-soluble vitamins, hormones, and persistent organic pollutants like PCBs and organochlorine pesticides. Florisil is also used in the pharmaceutical industry for compound purification and in quality control procedures where precise separation of complex mixtures is required. Its reproducibility and high sample loading capacity make it a reliable choice in both analytical and preparative-scale applications.