Used as a reference standard in analytical laboratories for the detection and quantification of dichloroacetic acid in environmental samples, drinking water, and biological fluids. It is essential in monitoring disinfection byproducts in water treatment processes, where chlorination can lead to the formation of haloacetic acids. Also employed in research studies related to metabolism, particularly in investigations of mitochondrial function and pyruvate dehydrogenase kinase inhibition. Its role as a standard ensures accuracy and reliability in chromatographic and mass spectrometric methods.