2-(4-Chlorophenoxy)-2-methylpropionic acid, also known as clofibric acid, is primarily utilized as a research compound in pharmacology, toxicology, and biochemistry. It serves as a potent agonist of peroxisome proliferator-activated receptor alpha (PPARα), which regulates lipid metabolism and fatty acid oxidation. Clofibric acid is the active metabolite of clofibrate, a fibrate-class hypolipidemic drug used to treat hyperlipidemia by lowering cholesterol and triglyceride levels. In research, it is employed to induce peroxisome proliferation in animal models, facilitating studies on liver function, carcinogenesis, and metabolic disorders. Additionally, it acts as an intermediate in the synthesis of other PPAR agonists and related pharmaceutical agents. Due to its specific biological activity, it is handled with care in laboratory settings.