Chrysin is used in dietary supplements for its antioxidant properties, supporting cellular health and reducing oxidative stress. It is commonly found in formulations aimed at promoting relaxation and sleep due to its interaction with neurotransmitter systems, such as GABA. In skincare products, it provides anti-inflammatory benefits, helping to soothe irritation and protect against environmental damage, while also inhibiting tyrosinase to reduce melanin production, making it suitable for addressing hyperpigmentation, freckles, or dark spots.

Chrysin is investigated for potential support in hormone balance, particularly as an aromatase inhibitor that modulates estrogen metabolism by preventing the conversion of testosterone to estrogen, which may benefit male hormonal health and physical performance. It is also explored in research for its possible role in supporting immune function and metabolic health. However, chrysin has limitations in bioavailability and absorption, leading to ongoing research on improved delivery methods, such as nano-carriers or structural modifications to enhance water solubility.