Used as a titrant in non-aqueous acid-base titrations for the determination of weak organic acids, especially in pharmaceutical analysis. Commonly applied in the quality control of drugs such as sulfonamides, barbiturates, and other acidic active pharmaceutical ingredients. Also employed in Karl Fischer titration for water content determination when working with samples that require a non-aqueous environment. Its role as a strong organic base makes it suitable for standardizing acid solutions in analytical chemistry laboratories.