Chloropyramine hydrochloride is primarily used as an antihistamine to treat allergic conditions. It helps alleviate symptoms such as itching, rashes, and hives by blocking histamine receptors in the body. It is also effective in managing allergic conjunctivitis and dermatitis. Additionally, it can be used to reduce allergic reactions caused by insect bites or certain medications. In some cases, it is administered as a sedative due to its mild calming effects. It is commonly found in topical creams, ointments, and oral formulations for ease of use.