Used as a versatile reagent in organic synthesis, particularly for introducing the isothiocyanate functional group. It reacts smoothly with amines to form thioureas, which are valuable intermediates in pharmaceuticals and agrochemicals. Its silyl group enhances reactivity and selectivity in various transformations, making it useful in the preparation of heterocyclic compounds. Commonly employed in mild reaction conditions, it is compatible with sensitive functional groups, allowing its use in complex molecule synthesis. Also utilized in the modification of peptides and nucleosides where selective derivatization is required.